Electric Literature of 88149-49-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 88149-49-9, name is 2,6-Dibromo-4-(trifluoromethoxy)aniline belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
The acid chloride reaction is completed, and 90.5 g (0.27 mol) of 2,6-dibromo-4-trifluoromethoxyaniline is added to the reaction vessel. Add catalyst 2 g of zinc chloride (0.015 mol) and benzoyl peroxide 2.5g (0.01mol), Rinse at 90 ° C for 4 h, The amidation incubation reaction is carried out. (3) Post-treatment: After the amidation reaction was completed, 80 mL of toluene was removed under reduced pressure, 100 mL of water was added, and 20 mL of toluene was removed under reduced pressure, and the temperature was lowered to 40 ° C. Filtration to obtain 124.9 g of solid thiazolamide. The purity was 96.7percent, and the yield was 91.5percent.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,6-Dibromo-4-(trifluoromethoxy)aniline, other downstream synthetic routes, hurry up and to see.