Application of 2734-70-5,Some common heterocyclic compound, 2734-70-5, name is 2,6-Dimethoxyaniline, molecular formula is C8H11NO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: To a mixture of benzoic acids 4 (7) (4 mmol),1-ethyl-3-(3-dimethyllaminopropyl) carbodiimide hydrochloride (4.8 mmol) and N-hydroxybenzotrizole (0.48 mmol) wereadded amines (4.8 mmol) at room temperature. The reaction mixture was stirredfor overnight and washed with water successively. The organic layer was driedover anhydrous sodium sulfate. Then the solvent was removed in vacuo to affordcrude compounds 5 (8).
The synthetic route of 2734-70-5 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Li, Jiling; Wu, Dang; Xu, Xiaoyong; Huang, Jin; Shao, Xusheng; Li, Zhong; Bioorganic and Medicinal Chemistry Letters; vol. 26; 13; (2016); p. 3064 – 3066;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem