Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 592-55-2, name is 1-Bromo-2-ethoxyethane, A new synthetic method of this compound is introduced below., Recommanded Product: 1-Bromo-2-ethoxyethane
0.24 g (10 mmol) of sodium hydride and 15 ml of N, N-dimethylformamide were added to a 50 ml round bottom flask at room temperatureStir for 10 minutes then add 2.5 g (10 mmol) of compound 2 and 10 mmol2-bromoethylether and trace detection by TLC to the end of the reaction. The reaction mixture was then poured into 500 ml of ice water and extracted three times with 100 ml of ethyl acetate. The organic phases were combined and the solvent was evaporated to dryness. The resulting residue was subjected to silica gel column chromatography Purification (V dichloromethane: V methanol = 100: 1) gave compound 3 (2.4 g, 76% yield).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Guangxi Normal University; Chen Zhenfeng; Liang Hong; Liu Yancheng; Lu Xing; Li Liangping; (13 pag.)CN106632414; (2017); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem