Adding a certain compound to certain chemical reactions, such as: 34967-24-3, name is 3,5-Dimethoxybenzyl amine, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 34967-24-3, Recommanded Product: 34967-24-3
To a stirred solution of 2,4 dichloro-pyrido [2,3-d] pyrimidine (1.3 g, 6.7 mmol) and 3, 5-dimethoxybenzylamine (1.1 g, 6.7 mmol) in 30 mL EtOH at RT was added TEA (4 mL, 28.7 mmol). A precipitate formed that was filtered off and washed with cold EtOH followed by hexanes to give 1.8 g of the title compound (82%) as a solid. mp 185C (dec).’H-NMR (DMSO-d6) 8 : 9.5 (t, 1H), 8. 9 (dd, 1H), 8.7 (dd, 1H), 7.5 (m, 1H), 6.5 (d, 2H), 6.4 (t, 1H), 4.6 (d, 2H), 3.7 (s, 6H). MS (m/z, %): 331 (100).
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Reference:
Patent; PFIZER PRODUCTS INC.; WO2005/61497; (2005); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem