Related Products of 22483-09-6, These common heterocyclic compound, 22483-09-6, name is 2,2-Dimethoxyethanamine, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
100 g of aminoacetaldehyde dimethyl acetal and 146 g of benzaldehyde are added to 2.5 liters of toluene, heated to reflux for 16 hours, and concentrated.The residue was dissolved in 1.8 L of methanol, 45 g of sodium borohydride was slowly added in portions, and the mixture was stirred at room temperature for 5 hours.Saturated ammonium chloride solution was added and extracted with ethyl acetate, followed by liquid separation, drying,Concentration gave 162 g of N-benzyl-2,2-dimethoxyethanamine and the crude product was used in the next reaction without purification.
Statistics shows that 2,2-Dimethoxyethanamine is playing an increasingly important role. we look forward to future research findings about 22483-09-6.
Reference:
Patent; Hunan Huateng Pharmaceutical Co., Ltd.; Bu Gonggaofamingren; (6 pag.)CN107778208; (2018); A;,
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