Electric Literature of 101-55-3,Some common heterocyclic compound, 101-55-3, name is 1-Bromo-4-phenoxybenzene, molecular formula is C12H9BrO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Nanoporous metal gold catalyst (9.8 mg, 0.05 mmol),Ethanol (1.5mL) and 4-bromophenyl phenyl ether(62.27mg, 0.25mmol),Cesium carbonate (364.3 mg, 1.125 mmol) was added to the reaction vessel, and hydrogen (40 bar) was introduced.Heating and stirring, the reaction temperature is controlled at 100 C,The reaction time is controlled at 90h.The reaction solution is extracted with water,Obtained 39.1 mg of biphenyl,The yield was 92%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-Bromo-4-phenoxybenzene, its application will become more common.
Reference:
Patent; Dalian University of Technology; Bao Ming; Zhao Yuhui; Feng Xiujuan; Yu Xiaoqiang; Zhang Sheng; (13 pag.)CN109608297; (2019); A;,
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