Related Products of 50868-73-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 50868-73-0 name is 2-Methoxy-6-methylaniline, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
b) Preparation of intermediate 4; 3.3 g of intermediate 3 (24.1 mmoles) were dissolved in acetic acid (15 ml). Iodine monochloride (5.87g, 36 mmoles) was added. The mixture was stirred at room temperature for 30 minutes and was evaporated. The residue was suspended in an aqueous solution of Na2CC>3 and was extracted with dichloromethane. After drying the dichloromethane extract on MgSCU, it was evaporated and the residue was purified on a silica gel column using dichloromethane as eluent. Yield : 0.758g (13%) of intermediate 4 (CI-MS : 264 [M+H]+).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Methoxy-6-methylaniline, and friends who are interested can also refer to it.
Reference:
Patent; JANSSEN PHARMACEUTICA N.V.; ARTS, Frank, Xavier, Jozef, Herwig; WO2006/15985; (2006); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem