Some common heterocyclic compound, 36865-41-5, name is 1-Bromo-3-methoxypropane, molecular formula is C4H9BrO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 36865-41-5
76.4 m76.4 mmol), l-bromo-3-methoxy-propane ( 12.9 g, 84 mmol ), K2CO3 (22 g, 21 53 mmol) and DMF (50 ml.). The resultant mixture was stirred at 50 C for 3 hours, and then to the resulting mixture was added ethyl acetate and water. The organic phase was separated, and then dried over anhydrous a2S04 and concentrated to give 4-bromo- 1 -methoxy-2-(3- methoxypropoxy)benzene (23 g).mol), l-bromo-3-methoxy-propane ( 12.9 g, 84 mmol ), K2CO3 (22 g, 21 53 mmol) and DMF (50 ml.). The resultant mixture was stirred at 50 C for 3 hours, and then to the resulting mixture was added ethyl acetate and water. The organic phase was separated, and then dried over anhydrous a2S04 and concentrated to give 4-bromo- 1 -methoxy-2-(3- methoxypropoxy)benzene (23 g).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 36865-41-5, its application will become more common.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; HAN, Xingchun; JIANG, Min; WANG, Jianhua; ZHOU, Chengang; WANG, Yongguang; YANG, Song; (135 pag.)WO2016/71215; (2016); A1;,
Ether – Wikipedia,
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