Synthetic Route of 91-16-7,Some common heterocyclic compound, 91-16-7, name is 1,2-Dimethoxybenzene, molecular formula is C8H10O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
That is,A 30 mL Schlenk tube was charged with 1,2-dimethoxybenzene (76 muL, 0.6 mmol)GO containing 50.66 w% of oxygen (100 mg)And boron trifluoride-ethyl ether complex (2.0 mL, 16.2 mmol) were charged,And reacted at 60 C. for 8 hours.Here, in GO,The amount of potassium permanganate to be used at the time of synthesis of GO is set to 5 times the amount of potassium permanganate used in Example 7 is used.After the reaction, the GO was crushed with ultrasonic waves, and the filtrate was suction filtered while washing with chloroform, the filtrate was separated with chloroform and water, the organic layer was filtered with folded folded paper and the solvent was distilled off under reduced pressure with an evaporator And dried under reduced pressure. The yield was 83%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,2-Dimethoxybenzene, its application will become more common.
Reference:
Patent; OKAYAMA UNIVERSITY; NISHINA, YUTA; MORIOKU, KUMIKA; (13 pag.)JP2017/31106; (2017); A;,
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