Adding a certain compound to certain chemical reactions, such as: 39021-83-5, name is 1,4-Dimethoxy-2,3-dimethylbenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 39021-83-5, name: 1,4-Dimethoxy-2,3-dimethylbenzene
2.1.b 1-(chloromethyl)-2,5-dimethoxy-3,4-dimethylbenzene In a round bottom flask, methoxy- protected hydroquinone (1.10 g, 6.62 mmol) was dissolved in conc. HCl and stirred at rt. ZnCl2 (0.90 g, 6.62 mmol) and paraformaldehyde (0.27 g, 7.9 mmol) were then added and stirred at rt. After 2 h, water was added to the flask and the organics were extracted with ether (3*30 mL), dried over Na2SO4, and concentrated down to a green-brown solid. Flash column chromatography on silica gel in a solution of 2% ether:hexanes afforded an off-white solid that contained a 4:1 mixture of the inseparable mono- and dichloromethylquinone (1.12 g, 91%). This mixture was taken on to the next step without further purification.
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Reference:
Patent; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; US2007/203080; (2007); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem