Recommanded Product: 2,6-Dimethoxyanilino(oxo)acetic acidIn 2018, Mao, Runze;Frey, Adrian;Balon, Jonathan;Hu, Xile published 《Decarboxylative C(sp3)-N cross-coupling via synergetic photoredox and copper catalysis》. 《Nature Catalysis》published the findings. The article contains the following contents:
Here, a general strategy for amination of alkyl electrophiles by merging photoredox and copper catalysis was provided. Photoredox catalysis allowed the use of alkyl redox-active esters, recently established as a superior class of alkyl electrophiles, whereas copper catalysis enabled C(sp3)-N cross-coupling. Decarboxylative amination could be used for the synthesis of a diverse set of alkyl anilines R1NHR2 [R1 = Ph, 2-MeOC6H4, 2-pyridyl, etc; R2 = CH(Me)2, n-hexyl, cyclohexyl, etc.], with high chemoselectivity and functional-group compatibility. Rapid functionalization of amino acids, natural products and drugs was demonstrated.2,6-Dimethoxyanilino(oxo)acetic acid (cas: 2097273-59-9) were involved in the experimental procedure.
2,6-Dimethoxyanilino(oxo)acetic acid is one of ethers-buliding-blocks. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. Recommanded Product: 2,6-Dimethoxyanilino(oxo)acetic acid They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem