Falk, Eric; Gasser, Valentina C. M.; Morandi, Bill published the artcile< Synthesis of N-Alkyl Anilines from Arenes via Iron-Promoted Aromatic C-H Amination>, Category: ethers-buliding-blocks, the main research area is arene oxymethylammonium triflate iron catalyst regioselective amination; methyl arylamine preparation; tosyloxy phenylpropyl carbamate iron catalyst regioselective amination; tetrahydroquinoline preparation.
We report both an intermol. C-H amination of arenes to access N-methylanilines and an intramol. variant for the synthesis of tetrahydroquinolines. A newly developed, highly electrophilic aminating reagent was key for the direct synthesis of unprotected N-methylanilines from simple arenes. The reactions display a broad functional group tolerance and employ catalytic amounts of a benign iron salt under mild reaction conditions.
Organic Letters published new progress about Amination catalysts. 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Category: ethers-buliding-blocks.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem