《General Route to Purin-2-ylmagnesium Halides by Metal-Halogen Exchange in Dichloromethane》 was written by Gazzola, Silvia; Gordon, Malcolm R.; Lindell, Stephen D.. Product Details of 60656-87-3 And the article was included in Synlett in 2020. The article conveys some information:
Treatment of a solution of 2-iodopurines in dichloromethane with an ethereal solution of ethylmagnesium bromide at -5°C generated the corresponding purin-2-ylmagnesium bromide, which reacted with aldehydes to give the corresponding 2-(hydroxyalkyl)purines I [R1 = H, Cl; R2 = i-Pr, 4-MeC6H4; R3 = Ph, 2-furyl, CH2OBn, etc.] in 53-84% yield. Performing the same procedure in THF as solvent resulted either in extensive decomposition or rapid isomerization to give 8-(hydroxyalkyl)purine. In the experimental materials used by the author, we found 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Product Details of 60656-87-3)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Product Details of 60656-87-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem