In 2019,ChemCatChem included an article by Qi, Xinxin; Lai, Ming; Zhu, Min-Jie; Peng, Jin-Bao; Ying, Jun; Wu, Xiao-Feng. Safety of 1-Iodo-2-methoxybenzene. The article was titled 《1-Arylvinyl formates: A New CO Source and Ketone Source in Carbonylative Synthesis of Chalcone Derivatives》. The information in the text is summarized as follows:
1-Arylvinyl formates as a kind of new CO surrogate was explored for the first time. Most of the known CO precursors usually produced undesired residuals, which were to be removed. In this strategy, after CO release, the in-situ generated acetophenones from 1-arylvinyl formates were successfully applied as a good ketone source in the synthesis of chalcones with benzaldehydes via a palladium-catalyzed reductive carbonylation reaction. A variety of chalcones were isolated in satisfactory to good yields with good substrates compatibilities under mild conditions.1-Iodo-2-methoxybenzene(cas: 529-28-2Safety of 1-Iodo-2-methoxybenzene) was used in this study.
1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Safety of 1-Iodo-2-methoxybenzene
Referemce:
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Ether | (C2H5)2O – PubChem