On October 1, 2013, Liu, Qing; Zhao, Yufen; Fu, Hua; Cheng, Changmei published an article.Formula: C8H10BrNO The title of the article was Copper-catalyzed sequential N-arylation and aerobic oxidation: synthesis of quinazoline derivatives. And the article contained the following:
A novel and efficient copper-catalyzed cascade method for the synthesis of quinazoline derivatives was developed. The protocol uses readily available substituted (2-bromophenyl)methanamines and amidine hydrochlorides as the starting materials, inexpensive CuBr as the catalyst, and economical and environment friendly air as the oxidant, and the corresponding quinazoline derivatives were obtained in moderate to good yields. The procedure underwent sequential intermol. N-arylation, intramol. nucleophilic substitution and aerobic oxidation The experimental process involved the reaction of (2-Bromo-5-methoxyphenyl)methanamine(cas: 887581-09-1).Formula: C8H10BrNO
The Article related to bromobenzylamine amidine hydrochloride cascade arylation copper catalyst, quinazoline preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Formula: C8H10BrNO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem