On February 19, 2021, Fang, Xiaolan; Cao, Ji; Ding, Weijie; Jin, Huile; Yu, Xiaochun; Wang, Shun published an article.Electric Literature of 157869-15-3 The title of the article was Copper-Catalyzed Aerobic Oxidative Cyclization of 2-Alkynylanilines with Nitrosoarenes: Synthesis of Organic Solid Mechanoluminescence Compounds of 4-Oxo-4H-cinnolin-2-ium-1-ide. And the article contained the following:
An efficient Cu(I)/DMAP/air system for the one-pot synthesis of 4-oxo-4H-cinnolin-2-ium-1-ides I [R = Ph, 4-ClC6H4, 3-thienyl, etc.; R1 = H, 6-Me, 5-Cl, etc.; R2 = H, 4-Me, 4-Cl, 4-Br, 4-MeO], which were often difficult to prepare by traditional routes from substituted 2-alkynylanilines and nitrosoarenes, was developed. These 4-oxo-4H-cinnolin-2-ium-1-ides had practical applications as mechanoluminescent materials. Preliminary mechanistic experiments were performed and a plausible mechanism for this tandem process was proposed. The use of an inexpensive copper catalyst and mol. oxygen as the oxygen source and the oxidant made this an attractive green protocol with potential synthetic applications. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Electric Literature of 157869-15-3
The Article related to oxo cinnoliniumide green preparation, alkynylaniline nitrosoarene tandem aerobic oxidative cyclization copper catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Electric Literature of 157869-15-3
Referemce:
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Ether | (C2H5)2O – PubChem