Li, Qiao; Cai, Yun; Hu, Yuanyuan; Jin, Hongwei; Chen, Fener; Liu, Yunkui; Zhou, Bingwei published an article in 2021, the title of the article was Nickel-catalyzed cyclization of 1,7-enynes for the selective synthesis of dihydrocyclobuta[c]quinolin-3-ones and benzo[b]azocin-2-ones.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline And the article contains the following content:
A nickel-catalyzed cyclization of N-(o-ethynylaryl)acrylamides for selective syntheses of dihydrocyclobuta[c]quinolin-3-ones I [R1 = Ph, 2-MeOC6H4, 4-ClC6H4, etc.; R2 = H, Me, Ph; R3 = Me, Et, Bn, methoxymethyl; R4 = H, 7-Me, 6-Cl, etc.] and benzo[b]azocin-2-ones II [R5 = Ph, 4-MeC6H4, 3-thienyl, etc.; R6 = H, Me, Ph; R7 = Me, Bn, methoxymethyl; R8 = H, 8-Me, 8-CN, etc.] was reported. The two varied products I and II could be easily obtained by tuning the reaction temperature This reaction featured easy temperature-control, high efficiency and gram-scale synthesis. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Reference of 2-((4-Methoxyphenyl)ethynyl)aniline
The Article related to dihydrocyclobutaquinolinone chemoselective preparation, enyne cyclization nickel catalyst, benzoazocinone chemoselective preparation, cyclization enyne nickel catalyst, Heterocyclic Compounds (One Hetero Atom): Higher-Membered Rings and other aspects.Reference of 2-((4-Methoxyphenyl)ethynyl)aniline
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