1,8-Naphthalimide derivatives as probes for protein surface hydrophobicity was written by Betancourt, Frank;Valente, Alyssa;Yan, Hongbin. And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2021.Safety of 2-Methoxyethylamine The following contents are mentioned in the article:
Four 4-aryl-N-methoxyethyl-1,8-naphthalimide derivatives were synthesized and evaluated for their fluorescent properties. All four compounds, 4-(p-methoxy)- 3a, 4-(p-amino)- 3b, 4-(p-dimethylamino)- 3c, and 4-(p-acetamido)- 3d are highly fluorescent in chloroform, but their fluorescence intensity is drastically decreased in polar solvents such as DMSO and methanol. Derivative 3c, in particular, showed a 699-fold fluorescence quenching in methanol, as compared in chloroform at 10 μM dye concentration Furthermore, dilution of DMSO solutions of probes 3a, 3b and 3d with water led to drastic decrease in fluorescence intensity, and virtually complete fluorescence quenching in the case of 3d. In aqueous solutions containing 3a or 3b, the presence of bovine serum albumin led to 80- and 50-fold increases in fluorescence intensity, resp. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Safety of 2-Methoxyethylamine).
2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 2-Methoxyethylamine
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem