Indoles from 2-methylnitrobenzenes by condensation with formamide acetals followed by reduction: 4-benzyloxyindole (1H-indole, 4-(phenylmethoxy)-) was written by Batcho, Andrew D.;Leimgruber, Willy. And the article was included in Organic Syntheses in 1985.Name: 3-Methyl-4-nitroanisole This article mentions the following:
Indoles, substituted in the benzene ring, were prepared by reductive cyclization of nitrocinnamylamines. Thus, 2-methyl-3-nitrophenol was O-benzylated and treated with Me2NCH(OMe)2 and pyrrolidine to give a mixture of 2,6-O2N(PhCH2O)C6H3CH:CHR (R = pyrrolidino, NMe2), which was treated with N2H4-Raney Ni to give the indole I. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Name: 3-Methyl-4-nitroanisole).
3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Name: 3-Methyl-4-nitroanisole
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem