Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 57602-02-5, name is 1,14-Dibromo-3,6,9,12-tetraoxatetradecane, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 57602-02-5
Example 2 Synthesis of Double End-Substituted Pentaethyleneglycol-Sumatriptan (SMQT-02) Sumatriptan (236 mg, 0.8 mmol) is dissolved in 2 mL dry DMF, 60% NaH (32 mg, 0.8 mmol) is added, stirred and react 15 minutes, triethylene glycol 2-bromoethyl (145.6 mg, 0.4 mmol) is added, and reaction is performed overnight under nitrogen gas protection. Water is added to the above reaction liquid to quench the reaction, extraction is performed three times by using acetic ether, an organic phase is dried by using anhydrous sodium sulfate, concentrate goes through column separation to obtain 184 mg product, with a yield rate 58%. 1H-NMR (CDCl3): 2.34 (s, 12H), 2.70 (t, 4H), 2.72 (s, 6H), 2.94 (t, 4H), 3.06 (t, 4H), 3.40 (t, 4H), 3.49 (s, 12H), 4.35 (s, 4H), 6.98 (s, 2H), 7.11 (d, 2H), 7.23 (d, 2H), 7.60 (s, 2H), 8.91 (s, 2H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 57602-02-5.
Reference:
Patent; JENKEM TECHNOLOGY CO.,LTD.(TIANJIN); XU, Lihua; ZHAO, Xuan; FENG, Zewang; WANG, Jinliang; WANG, Zhenguo; (16 pag.)US2016/82117; (2016); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem