Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 16452-01-0, name is 3-Methoxy-4-methylaniline, A new synthetic method of this compound is introduced below., COA of Formula: C8H11NO
General procedure: Schiff bases 1-20 were synthesized from condensation ofcommercially available isatin with different aromatic aminesin a small amount of water in high yields [33, 34] (Scheme1). In a typical reaction, a mixture of isatin (1 mmol) anddifferent substituted aromatic amines (1 mmol) in smallamount of water were stirred at room temperature for 20-30h. The progress of reaction was monitored by TLC. The yellowcrystalline powder of Schiff bases was collected by filtration,washed with water and then dried to afford compounds1-20 in high yields. Recrystallization from ethanolafforded pure crystals. The structures of compounds 1-20were determined by employing different spectroscopic techniquesincluding 1H-NMR, EI MS, IR, and UV spectroscopyand purity was confirmed by CHN analysis.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Khan, Khalid Mohammed; Mughal, Uzma Rasool; Ambreen, Nida; Rama, Nasim Hasan; Naz, Farzana; Perveen, Shahnaz; Choudhary, Muhammad Iqbal; Letters in drug design and discovery; vol. 7; 10; (2010); p. 716 – 720;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem