New progress of cas: 2235-01-0 | Journal of Organic Chemistry 2021

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Application of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Banerjee, Isita;Ghosh, Keshab Ch;Oheix, Emmanuel;Jean, Marion;Naubron, Jean-Valere;Reglier, Marius;Iranzo, Olga;Sinha, Surajit published 《Synthesis of protected 3,4- and 2,3-dimercaptophenylalanines as building blocks for Fmoc-peptide synthesis and incorporation of the 3,4-analog in a decapeptide using solid-phase synthesis》 in 2021. The article was appeared in 《Journal of Organic Chemistry》. They have made some progress in their research.Application of 2235-01-0 The article mentions the following:

3,4-Dimercaptophenylalanines and 2,3-dimercaptophenylalanines have been synthesized for the first time by nucleophilic substitution of a protected aminomalonate on 3,4- and 2,3-dimercaptobenzyl bromide derivatives The dithiol functions were protected as thioketals, and the key precursors, diphenylthioketal-protected dimercaptobenzyl bromides, were synthesized via two distinct routes from either dihydroxy benzoates or toluene-3,4-dithiol. Racemic mixtures of the fully protected amino acids were separated by chiral HPLC into the corresponding enantiomers. The absolute configuration of both 3,4- and 2,3-analogs could be assigned based on X-ray crystallog. and VCD/DFT measurements. Thioketal groups were deprotected upon reaction with mercury oxide and aqueous tetrafluoroboric acid followed by treatment with H2S gas under an argon atm. to obtain the corresponding dimercapto amino acids. The optically pure L-Fmoc-protected (Fmoc = 9-fluorenylmethoxycarbonyl) 3,4-analog (S enantiomer) was successfully incorporated into a decapeptide using standard solid-phase peptide synthesis. Therefore, dithiolene-functionalized peptides are now accessible from a simple synthetic procedure, and this should afford new mol. tools for research into the catalysis, diagnostic, and nanotechnol. fields.Dimethoxydiphenylmethane (cas: 2235-01-0) were involved in the experimental procedure.

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Application of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem